The Filing Desk

ADMA Biologics vs Krystal Biotech

ADMA Biologics ADMA · Krystal Biotech KRYS · Biotechnology

ADMA Biologics reported revenue of $510 million in fiscal 2025, 1.3 times Krystal Biotech's $389 million in fiscal 2025. ADMA Biologics' revenue grew 19.6% in its latest year, and Krystal Biotech's grew 33.9%. ADMA Biologics had an operating margin of 37.5%, against 41.5% at Krystal Biotech. Free cash flow was $28 million at ADMA Biologics and $189 million at Krystal Biotech.

Side by side

ADMA BiologicsKrystal Biotech
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$510M$389M
Revenue growth19.6%33.9%
Revenue growth a year, last 5 years64.6%—
Gross margin57.4%—
Operating margin37.5%41.5%
Net margin28.8%52.6%
Free cash flow$28M$189M
Free cash flow margin5.5%48.5%
Return on capital39.5%43.6%
Net debt to EBITDA−0.1x−5.0x
Dividends and buybacks$32M$0M
Change in diluted share count0.6%0.7%
Last close$11.06$313.66
P/E at the last close15.8×39.3×
Insider trades, last 12 monthsbought $468,294, sold $1.6 millionsold $105.3 million
Piotroski F-score5 of 95 of 8
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
ADMA BiologicsKrystal Biotech
Operating margin
Percent of revenue
ADMA BiologicsKrystal Biotech
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
ADMA BiologicsKrystal Biotech

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the ADMA Biologics and Krystal Biotech pages.