The Filing Desk

Alkermes vs Collegium Pharmaceutical

Alkermes ALKS · Collegium Pharmaceutical COLL · Pharmaceuticals

Alkermes reported revenue of $1.5 billion in fiscal 2025, 1.9 times Collegium Pharmaceutical's $781 million in fiscal 2025. Alkermes' revenue fell 5.2% in its latest year, and Collegium Pharmaceutical's grew 23.6%. Alkermes had an operating margin of 17.2%, against 23.0% at Collegium Pharmaceutical. Free cash flow was $480 million at Alkermes and $328 million at Collegium Pharmaceutical.

Side by side

AlkermesCollegium Pharmaceutical
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$1.5B$781M
Revenue growth−5.2%23.6%
Revenue growth a year, last 5 years7.3%20.3%
Gross margin86.7%59.4%
Operating margin17.2%23.0%
Net margin16.4%8.1%
Free cash flow$480M$328M
Free cash flow margin32.5%42.0%
Return on capital—53.4%
Net debt to EBITDA—−0.4x
Dividends and buybacks$0M$25M
Change in diluted share count−0.3%−1.8%
Last close$44.44$23.21
P/E at the last close116.9×18.7×
Insider trades, last 12 monthssold $10.2 millionsold $7.2 million
Piotroski F-score—6 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
AlkermesCollegium Pharmaceutical
Operating margin
Percent of revenue
AlkermesCollegium Pharmaceutical
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
AlkermesCollegium Pharmaceutical

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Alkermes and Collegium Pharmaceutical pages.