The Filing Desk

Alnylam Pharmaceuticals vs Elanco

Alnylam Pharmaceuticals ALNY · Elanco ELAN · Pharmaceuticals

Elanco reported revenue of $4.7 billion in fiscal 2025, 1.3 times Alnylam Pharmaceuticals' $3.7 billion in fiscal 2025. Alnylam Pharmaceuticals' revenue grew 65.2% in its latest year, and Elanco's grew 6.2%. Free cash flow was $465 million at Alnylam Pharmaceuticals and $284 million at Elanco.

Side by side

Alnylam PharmaceuticalsElanco
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$3.7B$4.7B
Revenue growth65.2%6.2%
Revenue growth a year, last 5 years49.8%7.6%
Gross margin81.8%55.0%
Operating margin13.5%—
Net margin8.4%−4.9%
Free cash flow$465M$284M
Free cash flow margin12.5%6.0%
Return on capital—−0.1%
Net debt to EBITDA−3.4x5.2x
Dividends and buybacks$0M$0M
Change in diluted share count5.5%−0.2%
Last close$155.94$25.74
P/E at the last close66.9×—
Insider trades, last 12 monthssold $40.4 millionbought $2.6 million, sold $100,050
Piotroski F-score6 of 96 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
Alnylam PharmaceuticalsElanco
Operating margin
Percent of revenue
Alnylam PharmaceuticalsElanco
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
Alnylam PharmaceuticalsElanco

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Alnylam Pharmaceuticals and Elanco pages.