The Filing Desk

Alnylam Pharmaceuticals vs Perrigo

Alnylam Pharmaceuticals ALNY · Perrigo PRGO · Pharmaceuticals

Perrigo reported revenue of $4.3 billion in fiscal 2025, about the same as Alnylam Pharmaceuticals' $3.7 billion in fiscal 2025. Alnylam Pharmaceuticals' revenue grew 65.2% in its latest year, and Perrigo's fell 2.8%. Alnylam Pharmaceuticals had an operating margin of 13.5%, against -26.4% at Perrigo. Free cash flow was $465 million at Alnylam Pharmaceuticals and $145 million at Perrigo.

Side by side

Alnylam PharmaceuticalsPerrigo
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$3.7B$4.3B
Revenue growth65.2%−2.8%
Revenue growth a year, last 5 years49.8%0.8%
Gross margin81.8%35.1%
Operating margin13.5%−26.4%
Net margin8.4%−33.5%
Free cash flow$465M$145M
Free cash flow margin12.5%3.4%
Return on capital—−13.2%
Net debt to EBITDA−3.4x—
Dividends and buybacks$0M$159M
Change in diluted share count5.5%0.8%
Last close$155.94$15.85
P/E at the last close66.9×—
Insider trades, last 12 monthssold $40.4 millionbought $106,350, sold $0
Piotroski F-score6 of 94 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
Alnylam PharmaceuticalsPerrigo
Operating margin
Percent of revenue
Alnylam PharmaceuticalsPerrigo
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
Alnylam PharmaceuticalsPerrigo

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Alnylam Pharmaceuticals and Perrigo pages.