Amphstar Pharmaceuticals vs Collegium Pharmaceutical
Collegium Pharmaceutical reported revenue of $781 million in fiscal 2025, about the same as Amphstar Pharmaceuticals' $720 million in fiscal 2025. Amphstar Pharmaceuticals' revenue fell 1.6% in its latest year, and Collegium Pharmaceutical's grew 23.6%. Amphstar Pharmaceuticals had an operating margin of 19.5%, against 23.0% at Collegium Pharmaceutical. Free cash flow was $121 million at Amphstar Pharmaceuticals and $328 million at Collegium Pharmaceutical.
Side by side
| Amphstar Pharmaceuticals | Collegium Pharmaceutical | |
|---|---|---|
| Latest fiscal year | FY2025, Dec 31, 2025 | FY2025, Dec 31, 2025 |
| Revenue | $720M | $781M |
| Revenue growth | −1.6% | 23.6% |
| Revenue growth a year, last 5 years | 15.5% | 20.3% |
| Gross margin | 49.5% | 59.4% |
| Operating margin | 19.5% | 23.0% |
| Net margin | 13.6% | 8.1% |
| Free cash flow | $121M | $328M |
| Free cash flow margin | 16.8% | 42.0% |
| Return on capital | 9.9% | 53.4% |
| Net debt to EBITDA | 1.7x | −0.4x |
| Dividends and buybacks | $76M | $25M |
| Change in diluted share count | −7.4% | −1.8% |
| Last close | $25.47 | $23.21 |
| P/E at the last close | 15.1× | 18.7× |
| Insider trades, last 12 months | sold $1.7 million | sold $7.2 million |
| Piotroski F-score | 6 of 9 | 6 of 9 |
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.
Ten years
Revenue
US$ billions, fiscal years
Amphstar PharmaceuticalsCollegium Pharmaceutical
Operating margin
Percent of revenue
Amphstar PharmaceuticalsCollegium Pharmaceutical
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
Amphstar PharmaceuticalsCollegium Pharmaceutical
Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Amphstar Pharmaceuticals and Collegium Pharmaceutical pages.