The Filing Desk

Avantor vs Illumina

Avantor AVTR · Illumina ILMN · Life Sciences Tools & Services

Avantor reported revenue of $6.6 billion in fiscal 2025, 1.5 times Illumina's $4.3 billion in fiscal 2025. Avantor's revenue fell 3.4% in its latest year, and Illumina's fell 0.7%. Avantor had an operating margin of -3.8%, against 18.6% at Illumina. Free cash flow was $495 million at Avantor and $931 million at Illumina. Their fiscal years end in different months (December 31 and December 28), so the periods don't line up exactly.

Side by side

AvantorIllumina
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 28, 2025
Revenue$6.6B$4.3B
Revenue growth−3.4%−0.7%
Revenue growth a year, last 5 years0.5%6.0%
Gross margin32.6%66.1%
Operating margin−3.8%18.6%
Net margin−8.1%19.6%
Free cash flow$495M$931M
Free cash flow margin7.5%21.4%
Return on capital−2.0%20.3%
Net debt to EBITDA22.0x0.3x
Dividends and buybacks$75M$742M
Change in diluted share count−0.2%−1.9%
Last close$17.29$271.04
P/E at the last close—50.6×
Insider trades, last 12 monthsbought $8.7 million, sold $0bought $84,627, sold $592.9 million
Piotroski F-score5 of 98 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
AvantorIllumina
Operating margin
Percent of revenue
AvantorIllumina
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
AvantorIllumina

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Avantor and Illumina pages.