The Filing Desk

Biogen vs Vertex Pharmaceuticals

Biogen BIIB · Vertex Pharmaceuticals VRTX · Biotechnology

Vertex Pharmaceuticals reported revenue of $12.0 billion in fiscal 2025, 1.2 times Biogen's $9.9 billion in fiscal 2025. Biogen's revenue grew 2.2% in its latest year, and Vertex Pharmaceuticals' grew 8.9%. Free cash flow was $2.1 billion at Biogen and $3.2 billion at Vertex Pharmaceuticals.

Side by side

BiogenVertex Pharmaceuticals
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$9.9B$12.0B
Revenue growth2.2%8.9%
Revenue growth a year, last 5 years−6.0%14.1%
Gross margin75.7%86.2%
Operating margin—34.8%
Net margin13.1%32.9%
Free cash flow$2.1B$3.2B
Free cash flow margin20.7%26.6%
Return on capital7.3%31.5%
Net debt to EBITDA0.9x−1.5x
Dividends and buybacks$0M$2.0B
Change in diluted share count0.8%0.0%
Last close$252.26$517.49
P/E at the last close27.1×30.1×
Insider trades, last 12 monthsbought $585, sold $905,414sold $158.1 million
Piotroski F-score5 of 96 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
BiogenVertex Pharmaceuticals
Operating margin
Percent of revenue
BiogenVertex Pharmaceuticals
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
BiogenVertex Pharmaceuticals

Start a new comparison

Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Biogen and Vertex Pharmaceuticals pages.