The Filing Desk

Bio-Rad Laboratories vs Charles River Laboratories

Bio-Rad Laboratories BIO · Charles River Laboratories CRL · Life Sciences Tools & Services

Charles River Laboratories reported revenue of $4.0 billion in fiscal 2025, 1.6 times Bio-Rad Laboratories' $2.6 billion in fiscal 2025. Bio-Rad Laboratories' revenue grew 0.7% in its latest year, and Charles River Laboratories' fell 0.8%. Bio-Rad Laboratories had an operating margin of 1.8%, against 0.6% at Charles River Laboratories. Free cash flow was $375 million at Bio-Rad Laboratories and $518 million at Charles River Laboratories. Their fiscal years end in different months (December 31 and December 27), so the periods don't line up exactly.

Side by side

Bio-Rad LaboratoriesCharles River Laboratories
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 27, 2025
Revenue$2.6B$4.0B
Revenue growth0.7%−0.8%
Revenue growth a year, last 5 years0.3%6.5%
Gross margin51.9%—
Operating margin1.8%0.6%
Net margin29.4%−3.6%
Free cash flow$375M$518M
Free cash flow margin14.5%12.9%
Return on capital0.5%0.4%
Net debt to EBITDA−1.6x4.5x
Dividends and buybacks$296M$361M
Change in diluted share count−3.3%−4.0%
Last close$372.43$357.27
P/E at the last close46.6×—
Insider trades, last 12 monthssold $349,883bought $7,338, sold $52.1 million
Piotroski F-score5 of 94 of 8
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
Bio-Rad LaboratoriesCharles River Laboratories
Operating margin
Percent of revenue
Bio-Rad LaboratoriesCharles River Laboratories
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
Bio-Rad LaboratoriesCharles River Laboratories

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Bio-Rad Laboratories and Charles River Laboratories pages.