The Filing Desk

BioMarin Pharmaceutical vs Neurocrine Biosciences

BioMarin Pharmaceutical BMRN · Neurocrine Biosciences NBIX · Biotechnology

BioMarin Pharmaceutical reported revenue of $3.2 billion in fiscal 2025, about the same as Neurocrine Biosciences' $2.9 billion in fiscal 2025. BioMarin Pharmaceutical's revenue grew 12.9% in its latest year, and Neurocrine Biosciences' grew 21.4%. BioMarin Pharmaceutical had an operating margin of 12.7%, against 21.6% at Neurocrine Biosciences. Free cash flow was $725 million at BioMarin Pharmaceutical and $749 million at Neurocrine Biosciences.

Side by side

BioMarin PharmaceuticalNeurocrine Biosciences
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$3.2B$2.9B
Revenue growth12.9%21.4%
Revenue growth a year, last 5 years11.6%22.3%
Gross margin77.7%98.2%
Operating margin12.7%21.6%
Net margin10.8%16.7%
Free cash flow$725M$749M
Free cash flow margin22.5%26.2%
Return on capital5.8%25.6%
Net debt to EBITDA−2.0x−2.3x
Dividends and buybacks$0M$168M
Change in diluted share count0.3%−1.2%
Last close$55.75$145.87
P/E at the last close150.7×21.4×
Insider trades, last 12 monthssold $4.3 millionsold $77.9 million
Piotroski F-score5 of 96 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
BioMarin PharmaceuticalNeurocrine Biosciences
Operating margin
Percent of revenue
BioMarin PharmaceuticalNeurocrine Biosciences
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
BioMarin PharmaceuticalNeurocrine Biosciences

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the BioMarin Pharmaceutical and Neurocrine Biosciences pages.