The Filing Desk

Charles River Laboratories vs Medpace

Charles River Laboratories CRL · Medpace MEDP · Life Sciences Tools & Services

Charles River Laboratories reported revenue of $4.0 billion in fiscal 2025, 1.6 times Medpace's $2.5 billion in fiscal 2025. Charles River Laboratories' revenue fell 0.8% in its latest year, and Medpace's grew 20.0%. Charles River Laboratories had an operating margin of 0.6%, against 21.1% at Medpace. Free cash flow was $518 million at Charles River Laboratories and $682 million at Medpace. Their fiscal years end in different months (December 27 and December 31), so the periods don't line up exactly.

Side by side

Charles River LaboratoriesMedpace
Latest fiscal yearFY2025, Dec 27, 2025FY2025, Dec 31, 2025
Revenue$4.0B$2.5B
Revenue growth−0.8%20.0%
Revenue growth a year, last 5 years6.5%22.3%
Gross margin——
Operating margin0.6%21.1%
Net margin−3.6%17.8%
Free cash flow$518M$682M
Free cash flow margin12.9%26.9%
Return on capital0.4%—
Net debt to EBITDA4.5x−0.9x
Dividends and buybacks$361M$917M
Change in diluted share count−4.0%−7.8%
Last close$357.27$676.77
P/E at the last close—37.6×
Insider trades, last 12 monthsbought $7,338, sold $52.1 millionsold $436.7 million
Piotroski F-score4 of 84 of 8
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
Charles River LaboratoriesMedpace
Operating margin
Percent of revenue
Charles River LaboratoriesMedpace
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
Charles River LaboratoriesMedpace

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Charles River Laboratories and Medpace pages.