The Filing Desk

Cytokinetics vs Z Squared

Cytokinetics CYTK · Z Squared ZSQR · Biotechnology

Cytokinetics reported revenue of $88 million in fiscal 2025, 62.9 times Z Squared's $1 million in fiscal 2025. Cytokinetics had an operating margin of -695.4%, against -956.9% at Z Squared.

Side by side

CytokineticsZ Squared
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$88M$1M
Revenue growth376.6%—
Revenue growth a year, last 5 years9.5%—
Gross margin—86.8%
Operating margin−695.4%−956.9%
Net margin−891.6%−874.3%
Free cash flow−$535M—
Free cash flow margin−607.5%—
Return on capital——
Net debt to EBITDA——
Dividends and buybacks$0M$0M
Change in diluted share count—120.0%
Last close$53.69$3.36
P/E at the last close——
Insider trades, last 12 monthssold $51.4 million—
Piotroski F-score——
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
CytokineticsZ Squared
Operating margin
Percent of revenue
CytokineticsZ Squared
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
CytokineticsZ Squared

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Cytokinetics and Z Squared pages.