The Filing Desk

Halozyme vs Repligen

Halozyme HALO · Repligen RGEN · Biotechnology

Halozyme reported revenue of $1.4 billion in fiscal 2025, 1.9 times Repligen's $738 million in fiscal 2025. Halozyme's revenue grew 37.5% in its latest year, and Repligen's grew 16.4%. Halozyme had an operating margin of 33.6%, against 7.5% at Repligen. Free cash flow was $645 million at Halozyme and $94 million at Repligen.

Side by side

HalozymeRepligen
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$1.4B$738M
Revenue growth37.5%16.4%
Revenue growth a year, last 5 years39.2%15.0%
Gross margin83.6%52.3%
Operating margin33.6%7.5%
Net margin22.7%6.6%
Free cash flow$645M$94M
Free cash flow margin46.1%12.7%
Return on capital19.2%2.4%
Net debt to EBITDA4.2x−1.7x
Dividends and buybacks$342M$0M
Change in diluted share count−4.3%—
Last close$128.01$180.17
P/E at the last close37.3×—
Insider trades, last 12 monthssold $41.2 millionsold $14.2 million
Piotroski F-score5 of 9—
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
HalozymeRepligen
Operating margin
Percent of revenue
HalozymeRepligen
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
HalozymeRepligen

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Halozyme and Repligen pages.