The Filing Desk

Incyte vs Neurocrine Biosciences

Incyte INCY · Neurocrine Biosciences NBIX · Biotechnology

Incyte reported revenue of $5.1 billion in fiscal 2025, 1.8 times Neurocrine Biosciences' $2.9 billion in fiscal 2025. Incyte's revenue grew 21.2% in its latest year, and Neurocrine Biosciences' grew 21.4%. Incyte had an operating margin of 29.5%, against 21.6% at Neurocrine Biosciences. Free cash flow was $1.4 billion at Incyte and $749 million at Neurocrine Biosciences.

Side by side

IncyteNeurocrine Biosciences
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$5.1B$2.9B
Revenue growth21.2%21.4%
Revenue growth a year, last 5 years14.0%22.3%
Gross margin92.8%98.2%
Operating margin29.5%21.6%
Net margin25.0%16.7%
Free cash flow$1.4B$749M
Free cash flow margin26.4%26.2%
Return on capital79.4%25.6%
Net debt to EBITDA−2.2x−2.3x
Dividends and buybacks$0M$168M
Change in diluted share count−4.7%−1.2%
Last close$113.31$145.87
P/E at the last close16.0×21.4×
Insider trades, last 12 monthssold $58.3 millionsold $77.9 million
Piotroski F-score8 of 96 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
IncyteNeurocrine Biosciences
Operating margin
Percent of revenue
IncyteNeurocrine Biosciences
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
IncyteNeurocrine Biosciences

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Incyte and Neurocrine Biosciences pages.