The Filing Desk

Incyte vs United Therapeutics

Incyte INCY · United Therapeutics UTHR · Biotechnology

Incyte reported revenue of $5.1 billion in fiscal 2025, 1.6 times United Therapeutics' $3.2 billion in fiscal 2025. Incyte's revenue grew 21.2% in its latest year, and United Therapeutics' grew 10.6%. Incyte had an operating margin of 29.5%, against 46.9% at United Therapeutics. Free cash flow was $1.4 billion at Incyte and $1.0 billion at United Therapeutics.

Side by side

IncyteUnited Therapeutics
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$5.1B$3.2B
Revenue growth21.2%10.6%
Revenue growth a year, last 5 years14.0%16.5%
Gross margin92.8%87.9%
Operating margin29.5%46.9%
Net margin25.0%41.9%
Free cash flow$1.4B$1.0B
Free cash flow margin26.4%32.7%
Return on capital79.4%—
Net debt to EBITDA−2.2x—
Dividends and buybacks$0M$1.0B
Change in diluted share count−4.7%−1.2%
Last close$113.31$592.84
P/E at the last close16.0×21.2×
Insider trades, last 12 monthssold $58.3 millionbought $863,940, sold $1.4 billion
Piotroski F-score8 of 9—
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
IncyteUnited Therapeutics
Operating margin
Percent of revenue
IncyteUnited Therapeutics
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
IncyteUnited Therapeutics

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Incyte and United Therapeutics pages.