The Filing Desk

Inspire Medical Systems vs Penumbra

Inspire Medical Systems INSP · Penumbra PEN · Health Care Equipment

Penumbra reported revenue of $1.4 billion in fiscal 2025, 1.5 times Inspire Medical Systems' $912 million in fiscal 2025. Inspire Medical Systems' revenue grew 13.6% in its latest year, and Penumbra's grew 17.5%. Inspire Medical Systems had an operating margin of 5.6%, against 13.5% at Penumbra. Free cash flow was $78 million at Inspire Medical Systems and $175 million at Penumbra.

Side by side

Inspire Medical SystemsPenumbra
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$912M$1.4B
Revenue growth13.6%17.5%
Revenue growth a year, last 5 years51.2%20.2%
Gross margin85.4%67.1%
Operating margin5.6%13.5%
Net margin15.9%12.7%
Free cash flow$78M$175M
Free cash flow margin8.6%12.5%
Return on capital14.2%18.8%
Net debt to EBITDA−4.8x−2.5x
Dividends and buybacks$175M$0M
Change in diluted share count−2.6%0.1%
Last close$71.01$325.22
P/E at the last close15.6×79.9×
Insider trades, last 12 monthssold $665,952sold $11.1 million
Piotroski F-score5 of 97 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
Inspire Medical SystemsPenumbra
Operating margin
Percent of revenue
Inspire Medical SystemsPenumbra
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
Inspire Medical SystemsPenumbra

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Inspire Medical Systems and Penumbra pages.