The Filing Desk

Repligen vs TG Therapeutics

Repligen RGEN · TG Therapeutics TGTX · Biotechnology

Repligen reported revenue of $738 million in fiscal 2025, 1.2 times TG Therapeutics' $616 million in fiscal 2025. Repligen's revenue grew 16.4% in its latest year, and TG Therapeutics' grew 87.3%. Repligen had an operating margin of 7.5%, against 20.0% at TG Therapeutics. Free cash flow was $94 million at Repligen and −$25 million at TG Therapeutics.

Side by side

RepligenTG Therapeutics
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$738M$616M
Revenue growth16.4%87.3%
Revenue growth a year, last 5 years15.0%398.6%
Gross margin52.3%83.7%
Operating margin7.5%20.0%
Net margin6.6%72.6%
Free cash flow$94M−$25M
Free cash flow margin12.7%−4.0%
Return on capital2.4%29.0%
Net debt to EBITDA−1.7x0.4x
Dividends and buybacks$0M$91M
Change in diluted share count—0.7%
Last close$173.49$59.83
P/E at the last close—21.8×
Insider trades, last 12 monthssold $14.2 millionsold $437,650
Piotroski F-score—4 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
RepligenTG Therapeutics
Operating margin
Percent of revenue
RepligenTG Therapeutics
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
RepligenTG Therapeutics

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Repligen and TG Therapeutics pages.