The Filing Desk

Cytokinetics vs Xencor

Cytokinetics CYTK · Xencor XNCR · Biotechnology

Xencor reported revenue of $126 million in fiscal 2025, 1.4 times Cytokinetics' $88 million in fiscal 2025. Cytokinetics' revenue grew 376.6% in its latest year, and Xencor's grew 13.7%. Cytokinetics had an operating margin of -695.4%, against -141.3% at Xencor. Free cash flow was −$535 million at Cytokinetics and −$138 million at Xencor.

Side by side

CytokineticsXencor
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$88M$126M
Revenue growth376.6%13.7%
Revenue growth a year, last 5 years9.5%0.5%
Gross margin——
Operating margin−695.4%−141.3%
Net margin−891.6%−73.2%
Free cash flow−$535M−$138M
Free cash flow margin−607.5%−110.1%
Return on capital—−19.9%
Net debt to EBITDA——
Dividends and buybacks$0M$0M
Change in diluted share count—14.1%
Last close$53.69$35.75
P/E at the last close——
Insider trades, last 12 monthssold $51.4 millionsold $3.8 million
Piotroski F-score—3 of 8
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
CytokineticsXencor
Operating margin
Percent of revenue
CytokineticsXencor
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
CytokineticsXencor

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Cytokinetics and Xencor pages.