The Filing Desk

Gilead Sciences vs Regeneron Pharmaceuticals

Gilead Sciences GILD · Regeneron Pharmaceuticals REGN · Biotechnology

Gilead Sciences reported revenue of $29.4 billion in fiscal 2025, 2.1 times Regeneron Pharmaceuticals' $14.3 billion in fiscal 2025. Gilead Sciences' revenue grew 2.4% in its latest year, and Regeneron Pharmaceuticals' grew 1.0%. Gilead Sciences had an operating margin of 34.0%, against 24.9% at Regeneron Pharmaceuticals. Free cash flow was $9.5 billion at Gilead Sciences and $4.1 billion at Regeneron Pharmaceuticals.

Side by side

Gilead SciencesRegeneron Pharmaceuticals
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$29.4B$14.3B
Revenue growth2.4%1.0%
Revenue growth a year, last 5 years3.6%11.0%
Gross margin78.8%—
Operating margin34.0%24.9%
Net margin28.9%31.4%
Free cash flow$9.5B$4.1B
Free cash flow margin32.1%28.4%
Return on capital22.9%12.7%
Net debt to EBITDA1.4x−1.4x
Dividends and buybacks$5.9B$3.8B
Change in diluted share count0.0%−5.7%
Last close$158.69$807.67
P/E at the last close—20.0×
Insider trades, last 12 monthssold $85.8 millionsold $16.1 million
Piotroski F-score8 of 95 of 8
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
Gilead SciencesRegeneron Pharmaceuticals
Operating margin
Percent of revenue
Gilead SciencesRegeneron Pharmaceuticals
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
Gilead SciencesRegeneron Pharmaceuticals

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Gilead Sciences and Regeneron Pharmaceuticals pages.