Halozyme vs Harmony Biosciences
Halozyme reported revenue of $1.4 billion in fiscal 2025, 1.6 times Harmony Biosciences' $868 million in fiscal 2025. Halozyme's revenue grew 37.5% in its latest year, and Harmony Biosciences' grew 21.5%. Halozyme had an operating margin of 33.6%, against 24.0% at Harmony Biosciences. Free cash flow was $645 million at Halozyme and $348 million at Harmony Biosciences.
Side by side
| Halozyme | Harmony Biosciences | |
|---|---|---|
| Latest fiscal year | FY2025, Dec 31, 2025 | FY2025, Dec 31, 2025 |
| Revenue | $1.4B | $868M |
| Revenue growth | 37.5% | 21.5% |
| Revenue growth a year, last 5 years | 39.2% | 40.3% |
| Gross margin | 83.6% | 77.2% |
| Operating margin | 33.6% | 24.0% |
| Net margin | 22.7% | 18.3% |
| Free cash flow | $645M | $348M |
| Free cash flow margin | 46.1% | 40.1% |
| Return on capital | 19.2% | 48.9% |
| Net debt to EBITDA | 4.2x | — |
| Dividends and buybacks | $342M | $0M |
| Change in diluted share count | −4.3% | 1.2% |
| Last close | $128.01 | $36.83 |
| P/E at the last close | 37.3× | 11.9× |
| Insider trades, last 12 months | sold $41.2 million | sold $6.0 million |
| Piotroski F-score | 5 of 9 | 5 of 9 |
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.
Ten years
Revenue
US$ billions, fiscal years
HalozymeHarmony Biosciences
Operating margin
Percent of revenue
HalozymeHarmony Biosciences
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
HalozymeHarmony Biosciences
Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Halozyme and Harmony Biosciences pages.