Harmony Biosciences

HRMY · Nasdaq · Health Care · Financials, fiscal 2019 to 2025

HRMY · Last close · October 26, 2026

$36.83

Harmony Biosciences' revenue rose 21.5% to $868 million in fiscal 2025. Its operating margin was 24.0%, down from 26.7% a year earlier. Free cash flow was $348 million, up 59.1%. The diluted share count rose 1.2%.

HARMONY BIOSCIENCES HOLDINGS, INC. Latest fiscal year ended December 31, 2025 10-K filed February 24, 2026 · 0001104659-26-018859 Updated October 22, 2026

Revenue

$868M

21.5%

Operating margin

24.0%

2.7 pts

Net income

$159M

9.1%

Free cash flow

$348M

59.1%

Return on capital

48.9%

6.2 pts

Market cap

$2.2B

Oct 26 close

P/E

11.9x

On $3.09 EPS, 4 qtrs

Operating margin is operating income as a share of revenue. Free cash flow is cash from operations minus capital spending. Return on capital is after-tax operating income as a share of the money invested in the business: debt plus equity, minus cash. Market cap is the last closing share price times the latest diluted share count, so it is approximate. P/E is the last close divided by diluted earnings per share over the last four quarters, or the latest fiscal year where the quarters aren't available; there is none when the company made a loss.

About these figures. Harmony Biosciences' 2025 filing doesn't tag its depreciation and amortization, so net debt to EBITDA is blank for that year.

Charts show fiscal years, from the 10-K filings.

Revenue and margins

Revenue

US$ billions, fiscal years

Margins

Percent of revenue

GrossOperatingNetFree cash flow

Net income and earnings per share

From fiscal 2021 to 2025, earnings per share grew 47.0% a year and net income 46.3% a year, as buybacks cut the share count by 1%.

Net income

US$ billions, fiscal years; loss years in red.

Diluted earnings per share

US$ per share, fiscal years, restated for any stock splits; loss years in red.

Returns on capital

Return on capital and on equity

Percent. Return on capital is after-tax operating income over the money invested in the business (debt plus equity, minus cash); return on equity is net income over shareholders' equity. Both use the average of opening and closing balances.

Return on capitalReturn on equity

Cash flow

Free cash flow

US$ billions. Cash from operations minus capital expenditure; negative years in red.

Payouts and share count

Dividends and buybacks

US$ billions, cash paid in each fiscal year

DividendsShare buybacks

Diluted share count

Weighted-average diluted shares, millions

Valuation

Two ways to value Harmony Biosciences yourself, both starting from its filings: a discounted cash flow model and the price-to-earnings method.

Discounted cash flow (DCF)

A discounted cash flow (DCF) model values a business as the cash it may generate in future, discounted back to today. The starting figures come from Harmony Biosciences' 10-K (or, for net cash and shares, its latest 10-Q) and the assumptions are yours: start from one of three example scenarios, then change any figure to see what it implies for a share, and how that compares with the last share price.

Value per share on three example scenarios, from Harmony Biosciences' fiscal 2025 free cash flow of $348M, net cash of $612M at December 31, 2025 and 58 million diluted shares, from its filings. The scenarios are fitted to Harmony Biosciences: the base scenario's growth in years 1 to 5 is its revenue growth over the last 3 years, 25.6% a year, kept between 0% and 20%; the cautious and optimistic ones are lower and higher, and growth in years 6 to 10 is halfway to the long-run rate. The base scenario's discount rate is 12%: 11% for a cyclical or higher-risk business (Biotechnology), plus 1 point as a smaller company, worth $2.2B; the cautious and optimistic ones use a point more and a point less. Select one to load it into the calculator. These are the model's arithmetic on those assumptions, not a forecast or a price target.

From the filings

Starting free cash flow, US$ millions

Cash from operations minus capital spending in fiscal 2025.

Net cash, US$ millions

Cash and short-term investments minus debt and finance leases at December 31, 2025. Negative means net debt.

Diluted shares, millions

Weighted-average diluted shares in fiscal 2025.

Your assumptions

Start from

Fitted to Harmony Biosciences's own revenue growth, as above. Cautious: growth of 10% then 6% a year, 2% after year 10, a 13% discount rate. Base: growth of 20% then 11% a year, 2.5% after year 10, a 12% discount rate. Optimistic: growth of 25% then 14% a year, 3% after year 10, a 11% discount rate.

Free cash flow growth, years 1 to 5 (% a year)

Free cash flow growth, years 6 to 10 (% a year)

Growth after year 10 (% a year)Long-run growth forever after year 10. Usually close to inflation, and always below the discount rate.

Discount rate (% a year)The yearly return an investor wants for the risk. A higher rate gives a lower value.

Value per share on these assumptions

—

Last close, October 26, 2026: $36.83
Value on these assumptions, against the last close: —

Cash flows in years 1 to 10, valued today: —
Everything after year 10, valued today: —
Plus net cash: —
Share of value from after year 10: —

Projected free cash flow

US$ billions. Each column is one year's projected free cash flow, split into what it is worth today and the part removed by discounting.

Value todayRemoved by discounting

How the value changes with two assumptions

Value per share in US$, with the growth rates above. The highlighted cell matches the current assumptions.

How the model works. Free cash flow grows at the first rate for five years and the second rate for five more, and each year is discounted at the discount rate. Everything after year 10 is valued as year-10 cash flow × (1 + growth after year 10) ÷ (discount rate − growth after year 10), discounted back ten years. Net cash is added and the total is divided by diluted shares. The result depends entirely on the assumptions. It is not a forecast, a price target or a recommendation. The last close is the consolidated US closing price, from Databento.

Price-to-earnings (P/E) method

Another common way to value a company is to multiply its earnings per share by a price-to-earnings (P/E) multiple: the number of years of today's earnings an investor pays for a share. A higher multiple usually means investors expect earnings to grow. Choose a multiple, for example from similar companies, to see the value it gives.

Careful. Harmony Biosciences' P/E today, 11.9×, is less than half the example multiple. A gap that wide usually means one of two things: its latest earnings include large one-off items, such as a tax benefit or a gain on a sale, or investors expect its earnings to fall. Either way the examples can mislead, so they aren't set against the share price. Check the earnings in its latest filings before using them.

Value per share on three example scenarios, from Harmony Biosciences' earnings per share of $3.09 (over the last four quarters). Each grows earnings for a year at the cash flow scenarios' rates and applies a multiple to next year's earnings: 26.6×, the middle of Harmony Biosciences' own P/E today, its peers' median and its sector's median (its peers' median) for the base scenario, 20% less and more for the cautious and optimistic ones. The price is brought back a year at 13%, 12% and 11%. Select one to load it into the calculator. These are the model's arithmetic on those assumptions, not a forecast or a price target.

Earnings per share, US$

Diluted earnings per share over the four quarters to June 30, 2026, from the 10-Qs and 10-K.

P/E multiple

P/E today is the last close divided by the latest earnings per share, the four quarters' where available. Peers: Halozyme, ADMA Biologics.

Earnings growth in the years ahead (% a year) Starts at Harmony Biosciences' revenue growth over the last 3 years, 25.6% a year, kept between 0% and 20%, as the base scenario does.

Earnings per share in the years ahead, US$

Year 1Year 2Year 3Year 4Year 5

Type your own estimate for any year; the years after it carry on at the growth rate.

Apply the multiple to earnings

A multiple on a future year's earnings gives the price then, brought back to today at the discount rate below.

Discount rate (% a year) The yearly return an investor wants for the risk, as in the cash flow model.

Value per share today at this multiple

—

Last close, October 26, 2026: $36.83
Value at this multiple, against the last close: —
Harmony Biosciences' P/E at the last close: 11.9×

Company	Last close	Earnings per share	P/E today
HalozymeHALO	$128.01	$3.43	37.3×
ADMA BiologicsADMA	$11.06	$0.70	15.8×
Harmony BiosciencesHRMY	$36.83	$3.09	11.9×

How the P/E method works. Value per share is earnings per share times the multiple. On a future year's earnings, that gives the price in that year, which is brought back to today at the discount rate: price ÷ (1 + discount rate) for each year ahead. It is quick and easy to compare across companies, but it ignores debt and cash, and earnings can swing with one-off gains and charges, so a multiple says most about steady, profitable businesses. Like the cash flow model, the result depends entirely on the assumptions you choose. It is not a forecast, a price target or a recommendation.

Balance sheet

Fiscal year end	FY21	FY22	FY23	FY24	FY25
Cash and short-term investments	234	323	354	467	775
Debt incl. finance leases	192	192	194	179	164
Net debt (negative means net cash)	−42	−132	−160	−288	−612
Net debt to EBITDA	−0.4x	−0.9x	−0.7x	−1.3x	—
Debt to equity	1.0x	0.5x	0.4x	0.3x	0.2x
Interest coverage	3.6x	6.4x	8.1x	10.9x	14.2x
Current ratio	5.3x	5.1x	2.8x	3.3x	3.6x
Quick ratio	5.2x	5.0x	2.7x	3.3x	3.6x

US$ millions unless stated, at each fiscal year end. Net debt to EBITDA is debt minus cash, divided by operating income before depreciation and amortization: roughly how many years of those earnings the net debt equals. Debt to equity is debt as a multiple of shareholders' equity. Interest coverage is operating income divided by interest expense. The current ratio is current assets over current liabilities; the quick ratio leaves out inventory.

Insider trades

Over the 12 months between October 27, 2025 and October 26, 2026, no insider bought Harmony Biosciences shares on the open market, and 3 insiders sold $6.0 million, all of it under trading plans set up in advance.

Date	Insider	Trade	Shares	Price	Value	Filing
Sep 18, 2026	Kumar BudurChief Medical Officer	Sold plan	35,852	$43.05	$1.5 million	Form 4
Sep 17, 2026	Kumar BudurChief Medical Officer	Sold plan	800	$43.00	$34,400	Form 4
Sep 16, 2026	Kumar BudurChief Medical Officer	Sold plan	1,800	$43.01	$77,418	Form 4
Sep 8, 2026	Kumar BudurChief Medical Officer	Sold plan	28,454	$42.95	$1.2 million	Form 4
Sep 4, 2026	Kumar BudurChief Medical Officer	Sold plan	5,500	$41.98	$230,890	Form 4
Jan 26, 2026	Sandip KapadiaChief Financial Officer	Sold plan	3,746	$37.15	$139,164	Form 4
Jan 15, 2026	Sandip KapadiaChief Financial Officer	Sold plan	20,961	$35.92	$752,919	Form 4
Dec 12, 2025	Jeffrey M. DaynoPresident, CEO, Director	Sold plan	25,933	$40.11	$1.0 million	Form 4
Dec 5, 2025	Sandip KapadiaChief Financial Officer	Sold plan	20,000	$39.54	$790,800	Form 4
Nov 21, 2025	Sandip KapadiaChief Financial Officer	Sold plan	3,427	$35.00	$119,945	Form 4

Open-market purchases and sales by officers, directors and 10% owners, from their Form 4 filings with the SEC: one row per person, day and filing, at the day's average price. Grants, option exercises and shares withheld for tax aren't counted. Insiders buy and sell for many reasons, such as taxes, spreading their savings or a plan set up months earlier, so a trade on its own says little about where a company is heading. For information only, not investment advice. Insider trades at all companies

Piotroski F-score

The F-score counts how many of nine simple tests of profitability, funding and efficiency a company passed in a year (Piotroski, 2000). The more tests passed, the stronger the year: 8 or 9 is strong, 0 to 2 weak. Companies that report no gross profit are scored on the other eight.

Test	FY23	FY24	FY25
Net income is positive	Pass	Pass	Pass
Cash from operations is positive	Pass	Pass	Pass
Return on assets rose	Fail	Fail	Fail
Cash from operations exceeds net income	Pass	Pass	Pass
Debt fell relative to assets	Pass	Pass	Pass
Current ratio rose	Fail	Pass	Pass
Share count didn't rise	Pass	Pass	Fail
Gross margin rose	Fail	Fail	Fail
Revenue rose relative to assets	Fail	Pass	Fail
F-score	5 of 9	7 of 9	5 of 9
Accruals ratio	−12.2%	−8.2%	−16.7%

The accruals ratio is net income minus cash from operations, over average total assets.

Compare

Put Harmony Biosciences side by side with any other company we cover: revenue, growth, margins, cash flow and returns, with ten years of charts.

Similar companies

Company	Year	Revenue growth	Operating margin	Free cash flow margin	Return on capital	Net debt to EBITDA	F-score	Compare
Harmony Biosciences	FY25	21.5%	24.0%	40.1%	48.9%	—	5
Arrowhead Pharmaceuticals	FY25	23,258.2%	11.9%	18.9%	—	−5.5x	5	Compare
Repligen	FY25	16.4%	7.5%	12.7%	2.4%	−1.7x	—	Compare
Halozyme	FY25	37.5%	33.6%	46.1%	19.2%	4.2x	5	Compare
ADMA Biologics	FY25	19.6%	37.5%	5.5%	39.5%	−0.1x	5	Compare

Each company's latest fiscal year. Fiscal years end in different months, so the periods don't line up exactly. Free cash flow margin is free cash flow as a share of revenue. Net debt to EBITDA is explained under the balance sheet, and the F-score above.

7 years of figures

Fiscal year	FY19	FY20	FY21	FY22	FY23	FY24	FY25
Income statement
Revenue	6	160	305	438	582	715	868
Revenue growth	—	2,564.6%	91.2%	43.4%	32.9%	22.8%	21.5%
Gross profit	4	132	250	354	461	558	670
Research and development	70	19	30	71	76	146	190
Operating income	−146	17	88	120	192	191	208
Net income	−152	−37	35	182	129	146	159
Diluted EPS (US$)	−24.07	−2.48	0.58	2.97	2.13	2.51	2.71
Diluted shares (millions)	8	26	59	61	60	58	58
Cash flow
Cash from operations	−75	−3	99	144	219	220	348
Capital expenditure	0	0	0	0	0	1	0
Free cash flow	−76	−3	98	144	219	219	348
Dividends paid	0	0	0	0	0	0	0
Share buybacks	0	0	0	0	100	0	0
Acquisitions	0	0	0	0	37	0	0
Stock-based compensation	10	5	16	26	32	43	45
Balance sheet at fiscal year end
Cash and short-term investments	24	229	234	323	354	467	775
Debt incl. finance leases	98	194	192	192	194	179	164
Total assets	107	427	433	674	811	999	1,272
Total liabilities	118	330	247	271	344	340	401
Shareholders' equity	−423	97	186	403	467	659	870
Margins and ratios
Gross margin	73.7%	82.6%	81.8%	80.9%	79.2%	78.1%	77.2%
Operating margin	−2,433.8%	10.6%	28.7%	27.4%	33.0%	26.7%	24.0%
Net margin	−2,535.1%	−23.1%	11.3%	41.4%	22.1%	20.4%	18.3%
Free cash flow margin	−1,260.8%	−1.9%	32.2%	33.0%	37.6%	30.6%	40.1%
Return on capital	—	—	78.2%	57.8%	49.3%	42.7%	48.9%
Return on equity	—	—	24.4%	61.6%	29.6%	25.8%	20.8%
Return on assets	—	−13.8%	8.0%	32.8%	17.4%	16.1%	14.0%
Net debt to EBITDA	—	−1.3x	−0.4x	−0.9x	−0.7x	−1.3x	—

US$ millions unless stated. Where a later 10-K restated a year, the latest filed figure is shown. Download all figures (CSV, US$ millions)

Source: Harmony Biosciences' Form 10-K filings, from SEC EDGAR. For information only, not investment advice. The Filing Desk is not affiliated with Harmony Biosciences.