The Filing Desk

Harmony Biosciences vs Repligen

Harmony Biosciences HRMY · Repligen RGEN · Biotechnology

Harmony Biosciences reported revenue of $868 million in fiscal 2025, 1.2 times Repligen's $738 million in fiscal 2025. Harmony Biosciences' revenue grew 21.5% in its latest year, and Repligen's grew 16.4%. Harmony Biosciences had an operating margin of 24.0%, against 7.5% at Repligen. Free cash flow was $348 million at Harmony Biosciences and $94 million at Repligen.

Side by side

Harmony BiosciencesRepligen
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$868M$738M
Revenue growth21.5%16.4%
Revenue growth a year, last 5 years40.3%15.0%
Gross margin77.2%52.3%
Operating margin24.0%7.5%
Net margin18.3%6.6%
Free cash flow$348M$94M
Free cash flow margin40.1%12.7%
Return on capital48.9%2.4%
Net debt to EBITDA—−1.7x
Dividends and buybacks$0M$0M
Change in diluted share count1.2%—
Last close$36.83$180.17
P/E at the last close11.9×—
Insider trades, last 12 monthssold $6.0 millionsold $14.2 million
Piotroski F-score5 of 9—
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
Harmony BiosciencesRepligen
Operating margin
Percent of revenue
Harmony BiosciencesRepligen
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
Harmony BiosciencesRepligen

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Harmony Biosciences and Repligen pages.