The Filing Desk

Harmony Biosciences vs TG Therapeutics

Harmony Biosciences HRMY · TG Therapeutics TGTX · Biotechnology

Harmony Biosciences reported revenue of $868 million in fiscal 2025, 1.4 times TG Therapeutics' $616 million in fiscal 2025. Harmony Biosciences' revenue grew 21.5% in its latest year, and TG Therapeutics' grew 87.3%. Harmony Biosciences had an operating margin of 24.0%, against 20.0% at TG Therapeutics. Free cash flow was $348 million at Harmony Biosciences and −$25 million at TG Therapeutics.

Side by side

Harmony BiosciencesTG Therapeutics
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$868M$616M
Revenue growth21.5%87.3%
Revenue growth a year, last 5 years40.3%398.6%
Gross margin77.2%83.7%
Operating margin24.0%20.0%
Net margin18.3%72.6%
Free cash flow$348M−$25M
Free cash flow margin40.1%−4.0%
Return on capital48.9%29.0%
Net debt to EBITDA—0.4x
Dividends and buybacks$0M$91M
Change in diluted share count1.2%0.7%
Last close$33.11$59.83
P/E at the last close10.9×21.8×
Insider trades, last 12 monthssold $6.0 millionsold $437,650
Piotroski F-score5 of 94 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
Harmony BiosciencesTG Therapeutics
Operating margin
Percent of revenue
Harmony BiosciencesTG Therapeutics
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
Harmony BiosciencesTG Therapeutics

Start a new comparison

Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Harmony Biosciences and TG Therapeutics pages.