The Filing Desk

Merck vs Pfizer

Merck MRK · Pfizer PFE · Pharmaceuticals

Merck reported revenue of $65.0 billion in fiscal 2025, about the same as Pfizer's $62.6 billion in fiscal 2025. Merck's revenue grew 1.3% in its latest year, and Pfizer's fell 1.6%. Free cash flow was $12.4 billion at Merck and $9.1 billion at Pfizer.

Side by side

MerckPfizer
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$65.0B$62.6B
Revenue growth1.3%−1.6%
Revenue growth a year, last 5 years9.4%8.5%
Gross margin74.8%74.3%
Operating margin——
Net margin28.1%12.4%
Free cash flow$12.4B$9.1B
Free cash flow margin19.0%14.5%
Return on capital24.8%7.2%
Net debt to EBITDA1.2x3.2x
Dividends and buybacks$13.3B$9.8B
Change in diluted share count−1.3%0.2%
Last close$140.61$29.79
P/E at the last close111.6×39.2×
Insider trades, last 12 monthssold $72.0 millionbought $3.0 million, sold $134,661
Piotroski F-score4 of 96 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
MerckPfizer
Operating margin
Percent of revenue
MerckPfizer
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
MerckPfizer

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Merck and Pfizer pages.