The Filing Desk

AstraZeneca vs GSK

AstraZeneca AZN · GSK GSK · Pharmaceuticals

AstraZeneca reported revenue of $58.7 billion in fiscal 2025, and GSK £32.7 billion in fiscal 2025, in different currencies. AstraZeneca's revenue grew 8.6% in its latest year, and GSK's grew 4.1%. AstraZeneca had an operating margin of 23.4%, against 24.3% at GSK. Free cash flow was $11.8 billion at AstraZeneca and £6.4 billion at GSK.

Side by side

AstraZenecaGSK
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$58.7B£32.7B
Revenue growth8.6%4.1%
Revenue growth a year, last 5 years17.2%6.0%
Gross margin81.9%72.4%
Operating margin23.4%24.3%
Net margin17.4%17.5%
Free cash flow$11.8B£6.4B
Free cash flow margin20.0%19.6%
Return on capital16.8%23.9%
Net debt to EBITDA—1.4x
Dividends and buybacks$5.5B£3.9B
Change in diluted share count−0.1%−0.6%
Last close$172.06$51.10
P/E at the last close——
Insider trades, last 12 monthsbought $3,248, sold $2.2 million—
Piotroski F-score9 of 98 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
In each company's own currency, fiscal years
AstraZenecaGSK
Operating margin
Percent of revenue
AstraZenecaGSK
Free cash flow
In each company's own currency. Cash from operations minus capital expenditure.
AstraZenecaGSK

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the AstraZeneca and GSK pages.