The Filing Desk

Harmony Biosciences vs Novavax

Harmony Biosciences HRMY · Novavax NVAX · Biotechnology

Novavax reported revenue of $1.1 billion in fiscal 2025, 1.3 times Harmony Biosciences' $868 million in fiscal 2025. Harmony Biosciences' revenue grew 21.5% in its latest year, and Novavax's grew 64.7%. Harmony Biosciences had an operating margin of 24.0%, against 40.3% at Novavax. Free cash flow was $348 million at Harmony Biosciences and −$250 million at Novavax.

Side by side

Harmony BiosciencesNovavax
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$868M$1.1B
Revenue growth21.5%64.7%
Revenue growth a year, last 5 years40.3%18.8%
Gross margin77.2%93.5%
Operating margin24.0%40.3%
Net margin18.3%39.2%
Free cash flow$348M−$250M
Free cash flow margin40.1%−22.3%
Return on capital48.9%—
Net debt to EBITDA—−1.0x
Dividends and buybacks$0M$0M
Change in diluted share count1.2%13.7%
Last close$33.11$10.78
P/E at the last close10.9×—
Insider trades, last 12 monthssold $6.0 million—
Piotroski F-score5 of 95 of 9
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
Harmony BiosciencesNovavax
Operating margin
Percent of revenue
Harmony BiosciencesNovavax
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
Harmony BiosciencesNovavax

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Harmony Biosciences and Novavax pages.