The Filing Desk

Vir Biotechnology vs Xencor

Vir Biotechnology VIR · Xencor XNCR · Biotechnology

Xencor reported revenue of $126 million in fiscal 2025, 1.8 times Vir Biotechnology's $69 million in fiscal 2025. Vir Biotechnology's revenue fell 7.6% in its latest year, and Xencor's grew 13.7%. Vir Biotechnology had an operating margin of -699.2%, against -141.3% at Xencor. Free cash flow was −$397 million at Vir Biotechnology and −$138 million at Xencor.

Side by side

Vir BiotechnologyXencor
Latest fiscal yearFY2025, Dec 31, 2025FY2025, Dec 31, 2025
Revenue$69M$126M
Revenue growth−7.6%13.7%
Revenue growth a year, last 5 years−2.1%0.5%
Gross margin100.0%—
Operating margin−699.2%−141.3%
Net margin−638.9%−73.2%
Free cash flow−$397M−$138M
Free cash flow margin−578.5%−110.1%
Return on capital—−19.9%
Net debt to EBITDA——
Dividends and buybacks$0M$0M
Change in diluted share count1.7%14.1%
Last close$12.21$35.75
P/E at the last close——
Insider trades, last 12 monthssold $8.2 millionsold $3.8 million
Piotroski F-score—3 of 8
Amounts in each company's own currency, US$ unless marked (a foreign company may report in another), each company's latest fiscal year from its 10-K, or 20-F or 40-F for a foreign company. Growth rates compare with the year before; the five-year rate is the average a year. Free cash flow is cash from operations minus capital spending; return on capital is after-tax operating income over the money invested in the business; P/E is the last close over the latest earnings per share. Banks are measured differently (return on equity, efficiency ratio), so some rows apply to one company only.

Ten years

Revenue
US$ billions, fiscal years
Vir BiotechnologyXencor
Operating margin
Percent of revenue
Vir BiotechnologyXencor
Free cash flow
US$ billions. Cash from operations minus capital expenditure.
Vir BiotechnologyXencor

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Source: the companies' Form 10-K filings, from SEC EDGAR, and the last close. For information only, not investment advice: the figures describe results, not which company is the better investment. The Filing Desk is not affiliated with either company. Full figures on the Vir Biotechnology and Xencor pages.